Context

We are seeking a candidate for a research associate position in molecular biology. The successful candidate will take part in an ongoing European H2020 project aimed at developing a biosensing platform for multiplex detection at single-cell level of biomarkers linked to cancer metastasis.

Working Environment

The position is open at the MICALIS institute (INRAE, University of Paris-Saclay), a research unit of more than 350 researchers developing multidisciplinary approaches and promoting microbial systems biology towards the development of synthetic biology applications for health and biotechnology. Within MICALIS, the recruiting research team specializes in developing whole-cell and cell-free synthetic biology for metabolic pathway and biosensor engineering to produce biologically active molecules and monitor disease biomarkers.

Key points of our working environment :

• Modern offices
• Meals provided
• Wellness programs
• opportunities for career development
• multidisciplinary approaches
• teamworking

Job Description

The person recruited will be responsible for engineering pathways that upon biomarker detection trigger the production of chemical signals simultaneously detectable with high sensitivity by surface-enhanced Raman scattering (SERS).The work will involve (i) design of pathway producing SERS detectable molecules (ii) engineering and benchmarking the designed pathways in an E. coli strain (iii) integrating the engineered pathways with biosensing devices develop by other project partners of the EU project. To achieve these tasks the successful candidate will benefit from several years of experience since the recruiting team has developed connecting biosensing devices with metabolic pathways.

(For more information : https://www.jfaulon.com/biosensor/)

Applicants’ profile

• Applicants should have a master or a Ph.D. degree, preferably with working experience, in one or more of molecular biology, genome engineering, metabolic engineering systems & synthetic biology.

• Essential skills required to include experimental protocols and analytical techniques used in molecular biology. Experience in designing and engineering metabolic pathways or biosensing devices are desirable.

The position is open for 12 months from September 1, 2023.

The appointee will be hired through fixed-term contracts in accordance with the French legislation.

A competitive salary will be proposed based on qualifications and experience.